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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787f4b677e98df6eed64e8d4c3ec4a7f9db7a839a12efe4559f8dd4193e015c5' 
  AND token = 'x+pPvKrO6ZQQuSBp99iyyT+GeVRsbI2h37my2Av5Qj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}