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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d21a2d7ce5169f0fde0d7b9d3e56d39497ebf1f5be64042f57937446437d7b' 
  AND token = 'ZUgEHKn5N/cSHCKrZ420JVxtFa1vXjJ32skX9HH8/Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}