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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1860e829212666fb0f36a8c412f2bdc3f3ceff299396f9b1196b6aeea0c9f8c4' 
  AND token = 'RrrZanvZNLpi+MLDxtC+1uY+6+x9vQ+XqFn6ANN4rD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}