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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3de373e5df76dfc2ca9f5d0e071a7727688e73941329a540bc2018751e8525' 
  AND token = 'H4boD0N+ufd1C3CA4XbWTlsYY8UnU/Iglhc5iWgRRAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}