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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0b7224d1fa78e1b96694d12f230327b9cbda2fc8f3741169f5462823add587' 
  AND token = 'eeWSsHk3dTj2LjHGIYyJdgXYBSzWOF4Gu9Y5rf5H6+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}