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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f0872616feb71123d91072e8cf7cab5bfdfdb1a83c6120d5de12041bb80e4c' 
  AND token = 'exe0plE1PxPIeRNLDB3AVGiIAq33kFrj6mN1yepSMxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}