SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd204fa3f4849cbb85d14a2ecd62449d1d2d6329566c0080676832aeaddc7a2db' 
  AND token = 't1MMExG/adHypOPlh9toQATAsKZNCPyWuL3O32r6Y+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}