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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a21c32252cc0626cba461b4499b626faf759c2388b848b6201cabf57e9eb569' 
  AND token = 'wZdSZvukr2PcfD3g6vJmwjvvXM8kgw5i0B9uCkNBF0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}