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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86522745cf0dc4101342599d5767d075c8e88367492a60f3dd0c55644330aefc' 
  AND token = 'Bs4bPb1P9ZtxRJ+xWBbXbfshI27hTt9HG2ir5n9dlso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}