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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dc0746a3328cb4cde047c5a6fb5f3e875be66166b745eefeb571b63b9d3e93a' 
  AND token = '1KGJdGUd8NgUak5Kok3qxk/o/aKbjJF6j/Xri5DiIYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}