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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce5de1a25e8434c6e4abb8aaa20bb1835caa0aa179d106e91020255bd13de98' 
  AND token = 'wr17M8yluop4EnfMPsygUkvjf6GZn9KiqWWfUd0vncA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}