SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c364731b0186cb728a7d0b9217f38fbfd8f59b2090e2790620e7fa38807c21fb' 
  AND token = 'LbFVW2Arqb9tI+Z144h9BcZbU0VAmQ65mTKLVdFWDxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}