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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3123a3d44060fad2847c80bff3e1adf073b7f7d0add6d0457cb3c1aae59cb8c7' 
  AND token = 'RbeIsgJ+SWXf9LZgcNOL3JZGs0Rq2BYyVubBeve+PAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}