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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36301e07ed278db46afb350a4165edb809a830544d069665a71482c21274846c' 
  AND token = 'LzR+KQRpNZ4IBSQ9Qs5gaRFghGefR9hdFziHFNzbJas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}