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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd3b2de4c0130dcfe22a6c0f3d76756c788acc2b80d9abe711f8fbdb2da6a018' 
  AND token = '6WBsFy259W0689K+5s+/EwIxW/xc7xMDfjHVHHCEIvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}