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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e045de13cb2d21749ecd6f7483091aaa44e090f1be3f5232a851748402c5d4' 
  AND token = 'Bfe6+8PX0BUasZUowfOcjhEQpM0J1sr6CoVwIIrKwj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}