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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed9e9bd9280683286608bf303f0a94d0200acd26711f56e9493a627d1d8aef2' 
  AND token = 'xiRmir2wOfc6PDf98/HSxRA1FBdXZkJJ9ZhhDk8SRno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}