SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589dc7e88969e08e1a2110aa40090b36c46587a3e0de1bb717b0bf5751b290d1' 
  AND token = 'IU+nYE/UXfTjMyrMyFZMXmuz4WdKG/7oVj4FA8fo0kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}