SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380c56f540740c336fe8c7eb02410dc1737e12381fee102e381e7b3132af9abc' 
  AND token = '6PWZFoIA4mTV4RZ7D+wex7CULhZ9xUCf+BsgzKx6Gn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}