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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453539941c43c6375713473e9842c15ee6b2f4aa93c0a23a3f0606008fcf7b8e' 
  AND token = 'wXRjRx3B/5tvOeqPbT50sV+liu1413YL3ebwzbZQj/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}