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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5a79dc681003fe61028b20df6f9a0a934fbbabc3338a1fe3b7c0289a333552' 
  AND token = '0uQGs8/XjtH6Y94+KxaOxCECOuQWqYFkJis8PGLcyJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}