SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a81cd815c3e9b9ae1fe318023d4e752d2911e7ac526ac942ba0d78e7275582b' 
  AND token = '5Uc0xS2trYPgJMJdTvLeDSP0AxTrBULVYaUXxYEZU4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}