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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899ae4408ea8d09049a503e9e481fa290b94b99bc13d555fbeb22e50c3b0aa38' 
  AND token = 'POYeREz9Fn3he1Duyg54w+yUqT00AEd0i9CkUAUJjSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}