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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe4dbc31a2d9c383fb81f051e03215cf21587a69432b7656a332b10f018ac728' 
  AND token = 'Ulc4jWl2O6xpS4WLhFIy6CpfyCWzY46RNEyK7BVXtkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}