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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5827c6ed7a5c559717805ed3e29310ad65de82dde698ae80c687d86833b1aee' 
  AND token = 'xgSy/HwCRneFUiffjrVdJe8UH+jSrlENLe1AUF2hYso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}