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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f266eb0d20c7bf1354aaea003920c85405fad9038c2badffd3bbab94d6f84985' 
  AND token = 'l6XJ9Ll4Atoc2MBPXHeqK4i8CAdvt+VvFXuAdB7FXuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}