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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5b11ab4cb70a51669ac048c5830975515f81b6a6b888e6cb310d8f14b7bea2' 
  AND token = 'TSz3qmJ3sALv2T0IQ/sT2PdJzf2USEhL/XLZ4FmOPz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}