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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0c9437015ca1a6c31d7b98388ec76e4b61dda97e4c038d1afa2ee7267f4364' 
  AND token = '2Qrf+SDJaZVZ6FVxpsy0OfiIDwiis+W87IGz5u8uAjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}