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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182623459637ce44c0a5a69087a894f41db830f6a9f80ff3e86251da430c21a0' 
  AND token = 'Ighjd5LfmXF8iU76jO0xeI+tTcS37aB5iiX4U4jw2Ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}