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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37cc6dd7293af6252024a72a16ff177b37e4f386d50361b6ce7e4b67cc5a07ba' 
  AND token = 'RQ9daiwoVNOyP2aPU51ElPNtu2pWkhgz62fpUMFiQ4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}