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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6448a52876200d53355b021bc5b6abc4aad7aad1f8279d6d814e75d3bb6e7bf6' 
  AND token = 'NdOpZ15R3MNDO/R0HrHBaWjU3tuYAD656P5WzKfGZqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}