SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28ef88c56c56b201ba9222eff5e3c5d90e52d13172862cf400d86bac558c49f' 
  AND token = 'qd56iv3cHLoXRQii/tZXFiGlIpyv5JOr1bJxqUFGYgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}