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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34a5ceb8f314db2506c084b165b4c7c75606e3f3db4ad0123d2380f0b48af98f' 
  AND token = 'k+U6h6cjln9r4Y0bT37On/uCNY5ZWsnElFsiCx2+Y1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}