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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1a2bc4a1d82ff062e5f7ad109804688359c9d1079caa037fcfe0e91e6beb939' 
  AND token = 'rMWtylWMzvh+4PYkeEFYcfiFep1MmTOR7NL5RnJM5uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}