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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f269c8e4ba8a3d52d10bb57c08a09ded51023b087644148021641d665f1016' 
  AND token = '2oOeZtnAelRyf5IoEajchAvY6N4OgxHZ1eKkNowgliA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}