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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49bf560b626cf41083c423c323c65f15d1df892cec647fb1f75e768fc8c1a124' 
  AND token = 'wvFHf8pVWW/fGCSNYh1yjKfftfQoAbK4jEdj4tqJHVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}