SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d33c2a60ed5077022da3f08fe8bdbfdb966d89ad4d0bae9fbec37bc7e829b66' 
  AND token = 'Hxv7mTj3Jvml0haYzJUC8G2jwI/jbTpSteXbS2jdh2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}