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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb340a6d089a8d438adaf9b6111d2164fe013088cc59a34998f81ce18041d90' 
  AND token = 'LIR5MG1cHN0Ng5EbqBG5HnR+h6kLmyz1LJ1PQuy0j1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}