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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb5d588dc7d66669e4877685623f32ee0be1f909446c053e29da2f82dfa1a99' 
  AND token = '2yF2D9pIv0IM9fvMRT4xdchB7OieTbDLZ/JnqovbQ8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}