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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6f5ab486a2986e79305900ab998383d9f146c313f5a368d0b0418a3f24a0c5' 
  AND token = 'Gd0zoxOJIpXTnJg1cyxBW9lDgAolo1MzYxm+9PS16Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}