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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66456e2d03c3d916b8d669fef2b4e1dea8f75a7392b69bf2aaf1187640c6ffa0' 
  AND token = '/ipfPPgbqBlNOtUkWuWZcgsXAr4OH5CagADA1j8FB3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}