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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a42e03c55de3260cb3e75571968411040be5c26c3d189e5fb0c9014e5cb4c9' 
  AND token = 'Pv4xm6C9zxqCWJfCs5gT7zsaoXyUfoi88kwkgnxyReo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}