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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c3300cc2b9e591465be192ff0f19ac153cad988e0bd2c1f5c5d5165dd600cd' 
  AND token = 'fuuU1DPmwsdbozFrPcb59VMpp1qMGLhoYHNAfUOg3d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}