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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5128bcbd3e20888aa055c5c738cf51e73b7da7d78ac768539a56425c5c169ff5' 
  AND token = 'x5ElHkLoJqWE0LCjJZlWCCw3XBpANjCQxqtqkni0Vhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}