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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b77afaf3e67d5e1f34be812c4c6462b6c4185056eede9b8faafc1b5c3ffab467' 
  AND token = 'e3t3I67emdzjcW82SPqs/EHpdi5g/s0dcxcqcA836xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}