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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb103ee58fe277569e512a465998ad238508873a8c938ac53b72647a17e63b1a' 
  AND token = 'arLMi/KQUuLZ2JpcFcLGSPD/P9QPBq8gyQmUYkdEV2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}