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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf8f4c3fe6b3857cbed922ff271c5e4c811cfd8b5c88b484b9970436b2c3046' 
  AND token = 'rWdbu/MYSh07zmKJCzx0cOlubtRxW7JI5MBcqhmj7UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}