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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d47a3211d75454e0045921a31fb0a683a795dc5bc24438e93040670b88e82d' 
  AND token = 'tfLN+vB8evlIUAqHI0TOBWdy2jJp/ctyVQMPaRW3Tck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}