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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6781315219c090a6b252484e66ab32919d75fff5e8cbf6ec6f3bcd243d4fda45' 
  AND token = 'xeXgSGFArjHLjW2qd7PfJJ1vwJtT9sJ89nLs8DDUWEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}