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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0165d124ec4008491aaff694fc98f0af2999a2bd7a3437b2a1fadc138c49f9d3' 
  AND token = 'J2CF9xqRxKriqNRgJVcv61E/caPERD380jOUiM2capU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}